Jah you may want to consider this:
How do I force my torrents on Vuze to download/upload through the VPN?
To do this, you will need to make use of the Bind IP function which is both available on the Windows and the Mac.
First of all, you will need to enable the Advanced settings. To do this, navigate to Tools > Options > Mode and check Advanced.
After you have enabled it, go to Connection > Advanced Connection Settings
Finally, you will just need to enter the interface name of the TAP adaptor under Bind to local IP address or interface. Just enter the value of the TAP adaptor which can be referenced from the list of available interfaces listed in the same window. For Windows, it's usually begins with eth. As for the Mac, tun.